The O'Connells find themselves being chased around the world by the undead corrupt High Priest, Imhotep, and his lackey, Colin Weasler, while trying to get the Manacle of Osiris off of Alex O'Connell's wrist. This takes them around the world, trying to locate the lost scrolls of Thebes, the only things that can remove the manacle. The scrolls have to be destroyed to prevent Imhotep from possessing the manacle. In the second season, Alex is trained as a Medjai to combat the mummy, as well as facing new threats along the way. (2001 to 2003)
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